Immunology and Clinical Manifestations of Non-Clonal Mast Cell Activation Syndrome
نویسندگان
چکیده
منابع مشابه
Clonal mast cell activation syndrome with anaphylaxis to sulfites.
Sulfites are rarely suspected as causative agents of immediate-type hypersensitivity. We report on a 49-year-old male patient who developed recurrent severe hypotension after food ingestion. A diagnosis of monoclonal mast cell activation syndrome was established. In the double-blind, placebo-controlled food challenge, the patient reacted to potassium metabisulfite with anaphylaxis.
متن کاملMast cell activation syndrome: a newly recognized disorder with systemic clinical manifestations.
BACKGROUND Diagnostic criteria for mast cell (MC) activation syndrome have been recently proposed, but clinical studies to validate these criteria are lacking. OBJECTIVE We sought to determine the clinical manifestations of this newly recognized syndrome in a cohort of patients. METHODS We prospectively evaluated 18 patients seen at our institution with MC activation syndrome from 2006 to 2...
متن کاملMast cell activation syndrome
www.amepc.org/tau © Translational Andrology and Urology. All rights reserved. It has been over 30 years since the Interstitial Cystitis Association of America (ICA) was established in 1984. Although a great deal more is understood about interstitial cystitis/bladder pain syndrome (IC/BPS), the cause and cure of this condition remains unknown. One hypothesis regarding etiology that appears to ha...
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Background Allergic rhinitis is well known to be accompanied by inflammatory responses in the nasal wall and lumen including predominant infiltration of eosinophils, T cells and mast cells. With the discovery of IgE as the link between allergen exposure and mediator release, mast cells established their role as effector cells in the development and maintenance of allergic diseases. However, the...
متن کاملAdvances in the understanding and clinical management of mastocytosis and clonal mast cell activation syndromes
Clonal mast cell activation syndromes and indolent systemic mastocytosis without skin involvement are two emerging entities that sometimes might be clinically difficult to distinguish, and they involve a great challenge for the physician from both a diagnostic and a therapeutic point of view. Furthermore, final diagnosis of both entities requires a bone marrow study; it is recommended that this...
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ژورنال
عنوان ژورنال: Current Allergy and Asthma Reports
سال: 2012
ISSN: 1529-7322,1534-6315
DOI: 10.1007/s11882-012-0326-8